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Correlation of amyloid PET ligand florbetapir F 18 ((18)F-AV-45) binding with β-amyloid aggregation and neuritic plaque deposition in postmortem brain tissue
BACKGROUND: Florbetapir F 18 ((18)F-AV-45) is a positron emission tomography (PET) imaging ligand for the detection of amyloid aggregation associated with Alzheimer’s disease. Earlier data showed that florbetapir F 18 binds with high affinity to β-amyloid plaques in human brain homogenates (Kd = 3.7...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3286131/ https://ncbi.nlm.nih.gov/pubmed/22354138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WAD.0b013e31821300bc |
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