Optimization of Automated Radiosynthesis of [(18)F]AV-45: A New PET Imaging Agent for Alzheimer’s Disease

INTRODUCTION: Accumulation of β-amyloid (Aβ) aggregates in the brain is linked to the pathogenesis of Alzheimer’s disease (AD). Imaging probes targeting these Aβ aggregates in the brain may provide a useful tool to facilitate the diagnosis of AD. Recently, [(18)F]AV-45 ([(18)F]5) demonstrated high b...

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Detalhes bibliográficos
Main Authors: Liu, Yajing, Zhu, Lin, Plössl, Karl, Choi, Seok Rye, Qiao, Hongwen, Sun, Xiaotao, Li, Song, Zha, Zhihao, Kung, Hank F
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993015/
https://ncbi.nlm.nih.gov/pubmed/21055622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2010.05.001
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