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An updated radiosynthesis of [(18)F]AV1451 for tau PET imaging

BACKGROUND: [(18)F]AV1451 is a commonly used radiotracer for imaging tau deposits in Alzheimer’s disease (AD) and related non-AD tauopathies. Existing radiosyntheses of [(18)F]AV1451 require complex purifications to provide doses suitable for use in clinical imaging studies. To address this issue, w...

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Publicat a:EJNMMI Radiopharm Chem
Autors principals: Mossine, Andrew V., Brooks, Allen F., Henderson, Bradford D., Hockley, Brian G., Frey, Kirk A., Scott, Peter J. H.
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824695/
https://ncbi.nlm.nih.gov/pubmed/29503848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41181-017-0027-7
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