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Synthesis and evaluation of novel tropane derivatives as potential PET imaging agents for the dopamine transporter
A novel series of tropane derivatives containing a fluorinated tertiary amino or amide at the 2β position was synthesized, labeled with the positron-emitter fluorine-18 (T(1/2) = 109.8 min), and tested as potential in vivo dopamine transporter (DAT) imaging agents. The corresponding chlorinated anal...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378994/ https://ncbi.nlm.nih.gov/pubmed/22658558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.05.030 |
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