Synthesis, uptake mechanism characterization and biological evaluation of (18)F labeled fluoroalkyl phenylalanine analogs as potential PET imaging agents

INTRODUCTION: Amino acids based tracers represent a promising class of tumor metabolic imaging agents with successful clinical applications. Two new phenylalanine derivatives, p-(2-[(18)F]fluoroethyl)-L-phenylalanine (FEP, [(18)F]2) and p-(3-[(18)F]fluoropropyl)-L-phenylalanine (FPP, [(18)F]3) were...

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Hlavní autoři: Wang, Limin, Qu, Wenchao, Lieberman, Brian P., Plössl, Karl, Kung, Hank F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065024/
https://ncbi.nlm.nih.gov/pubmed/21220129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2010.07.005
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