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Synthesis and evaluation of (18)F labeled FET prodrugs for tumor imaging

INTRODUCTION: O-(2-[(18)F]fluoroethyl)-L-tyrosine (FET, [(18)F]1) is a useful amino-acid-based imaging agent for brain tumors. This paper reports the synthesis and evaluation of three FET prodrugs, O-(2-[(18)F]fluoroethyl)-L-tyrosyl-L-glycine (FET-Gly, [(18)F]2), O-(2-[(18)F]fluoroethyl)-L-tyrosyl-L...

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Autors principals: Wang, Limin, Lieberman, Brian P., Ploessl, Karl, Kung, Hank F.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895945/
https://ncbi.nlm.nih.gov/pubmed/24183614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2013.09.011
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