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Synthesis and evaluation of two novel 2-nitroimidazole derivatives as potential PET radioligands for tumor imaging

INTRODUCTION: Nitroimidazole (azomycin) derivatives labeled with radioisotopes have been developed as cancer imaging and radiotherapeutic agents based on the oncological hypoxic mechanism. By attaching nitroimidazole core with different functional groups, we synthesized new nitroimidazole derivative...

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Detalhes bibliográficos
Main Authors: Zha, Zhihao, Zhu, Lin, Liu, Yajing, Du, Fenghua, Gan, Hongmei, Qiao, Jinpin, Kung, Hank F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086661/
https://ncbi.nlm.nih.gov/pubmed/21531287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2010.11.001
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