p190RhoGEF (Rgnef) promotes colon carcinoma tumor progression via interaction with focal adhesion kinase

Focal adhesion kinase (FAK) functions downstream of integrins and growth factor receptors to promote tumor cell motility and invasion. In colorectal cancer, FAK is activated by amidated gastrin, a pro-tumorigenic hormone. However, it is unclear how FAK receives signals from the gastrin receptor or o...

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Bibliografiska uppgifter
Huvudupphovsmän: Yu, Hong-Gang, Nam, Ju-Ock, Miller, Nichol L. G., Tanjoni, Isabelle, Walsh, Colin, Shi, Lei, Kim, Linda, Chen, Xiao-Lei, Tomar, Alok, Lim, Ssang-Taek, Schlaepfer, David D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064514/
https://ncbi.nlm.nih.gov/pubmed/21224360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-2894
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