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Focal adhesion kinase: switching between GAPs and GEFs in the regulation of cell motility

SUMMARY: Focal adhesion (FA) kinase (FAK) is a cytoplasmic protein-tyrosine kinase involved in cytoskeleton remodeling, formation and disassembly of cell adhesion structures, and in the regulation of Rho-family GTPases. Therefore, FAK is widely accepted as an important promoter of directional cell m...

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Detalhes bibliográficos
Main Authors: Tomar, Alok, Schlaepfer, David D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754589/
https://ncbi.nlm.nih.gov/pubmed/19525103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2009.05.006
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