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p190RhoGEF (Rgnef) promotes colon carcinoma tumor progression via interaction with focal adhesion kinase
Focal adhesion kinase (FAK) functions downstream of integrins and growth factor receptors to promote tumor cell motility and invasion. In colorectal cancer, FAK is activated by amidated gastrin, a pro-tumorigenic hormone. However, it is unclear how FAK receives signals from the gastrin receptor or o...
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| Hauptverfasser: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064514/ https://ncbi.nlm.nih.gov/pubmed/21224360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-2894 |
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