Evidence for Direct Activation of mTORC2 Kinase Activity by Phosphatidylinositol 3,4,5-Trisphosphate

mTORC2 (mammalian target of rapamycin complex 2) plays important roles in signal transduction by regulating an array of downstream effectors, including protein kinase AKT. However, its regulation by upstream regulators remains poorly characterized. Although phosphatidylinositol 3,4,5-trisphosphate (...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Gan, Xiaoqing, Wang, Jiyong, Su, Bing, Wu, Dianqing
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064154/
https://ncbi.nlm.nih.gov/pubmed/21310961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.195016
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky