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The cAMP Effectors Epac and PKA are Involved in the Hepatic Cystogenesis of an Animal Model of ARPKD

PCK rats, an animal model of autosomal recessive polycystic kidney disease (ARPKD), develop cholangiocyte-derived liver cysts associated with increased intracellular adenosine 3′,5′-cyclic monophosphate (cAMP), the inhibition of which suppresses cyst growth. We hypothesized that elevated cAMP stimul...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Banales, Jesús M., Masyuk, Tatyana V., Gradilone, Sergio A., Masyuk, Anatoliy I., Medina, Juan F., LaRusso, Nicholas F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063896/
https://ncbi.nlm.nih.gov/pubmed/19065671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22636
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