Hepatic Cystogenesis Is Associated with Abnormal Expression and Location of Ion Transporters and Water Channels in an Animal Model of Autosomal Recessive Polycystic Kidney Disease

Polycystic kidney (PCK) rats are a spontaneous model of autosomal recessive polycystic kidney disease that exhibit cholangiocyte-derived liver cysts. We have previously reported that in normal cholangiocytes a subset of vesicles contain three proteins (ie, the water channel AQP1, the chloride channe...

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Auteurs principaux: Banales, Jesús M., Masyuk, Tatyana V., Bogert, Pamela S., Huang, Bing Q., Gradilone, Sergio A., Lee, Seung-Ok, Stroope, Angela J., Masyuk, Anatoliy I., Medina, Juan F., LaRusso, Nicholas F.
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2008
Sujets:
Regular Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626376/
https://ncbi.nlm.nih.gov/pubmed/18988797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080125
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