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Biliary Dysgenesis in the PCK Rat, an Orthologous Model of Autosomal Recessive Polycystic Kidney Disease

Hepatic polycystic disease occurs alone or in combination with polycystic kidney disease (PKD). In autosomal recessive PKD (ARPKD), liver lesions are the major cause of morbidity and mortality in older patients. ARPKD is caused by a mutation to PKHD1 and the PCK rat is an orthologous model of diseas...

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Main Authors: Masyuk, Tatyana V., Huang, Bing Q., Masyuk, Anatoliy I., Ritman, Erik L., Torres, Vicente E., Wang, Xiaofang, Harris, Peter C., LaRusso, Nicholas F.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618661/
https://ncbi.nlm.nih.gov/pubmed/15509540
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