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Systematic Evaluation of the Descriptive and Predictive Performance of Paediatric Morphine Population Models
PURPOSE: A framework for the evaluation of paediatric population models is proposed and applied to two different paediatric population pharmacokinetic models for morphine. One covariate model was based on a systematic covariate analysis, the other on fixed allometric scaling principles. METHODS: The...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer US
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3063866/ https://ncbi.nlm.nih.gov/pubmed/21153913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-010-0333-1 |
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