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Ethanol Is a Fast Channel Inhibitor of P2X4 Receptors

P2X receptors (P2XRs) are ion channels gated by synaptically released ATP. The P2X4 is the most abundant P2XR subtype expressed in the central nervous system and to date is the most ethanol-sensitive. In addition, genomic findings suggest that P2X4Rs may play a role in alcohol intake/preference. How...

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Detalhes bibliográficos
Main Authors: Ostrovskaya, Olga, Asatryan, Liana, Wyatt, Letisha, Popova, Maya, Li, Kaixun, Peoples, Robert W., Alkana, Ronald L., Davies, Daryl L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063738/
https://ncbi.nlm.nih.gov/pubmed/21212160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.176990
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