A POINT MUTATION IN THE ECTODOMAIN-TRANSMEMBRANE 2 INTERFACE ELIMINATES THE INHIBITORY EFFECTS OF ETHANOL IN P2X4 RECEPTORS

ATP-gated P2X4 receptors (P2X4R) are abundantly expressed in the CNS. However, little is known about the molecular targets for ethanol action in P2X4Rs. The current investigation tested the hypothesis that the ectodomain-TM interface contains residues that are important for the action of ethanol in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Popova, Maya, Asatryan, Liana, Ostrovskaya, Olga, Wyatt, Letisha R., Li, Kaixun, Alkana, Ronald L., Davies, Daryl L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809143/
https://ncbi.nlm.nih.gov/pubmed/19878433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06460.x
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