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Roles of Ectodomain and Transmembrane Regions in Ethanol and Agonist Action in Purinergic P2X2 and P2X3 Receptors
The present work investigated sites of ethanol action in ATP-gated P2X receptors (P2XRs) using chimeric strategies that exploited the differences in ethanol response between P2X2R (inhibition) and P2X3R (potentiation). We tested ethanol (10–200mM) effects on ATP- and α,β-methylene-ATP (α,β-meATP)-in...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2629788/ https://ncbi.nlm.nih.gov/pubmed/18639563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2008.06.044 |
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