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Ethanol Is a Fast Channel Inhibitor of P2X4 Receptors

P2X receptors (P2XRs) are ion channels gated by synaptically released ATP. The P2X4 is the most abundant P2XR subtype expressed in the central nervous system and to date is the most ethanol-sensitive. In addition, genomic findings suggest that P2X4Rs may play a role in alcohol intake/preference. How...

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Autors principals: Ostrovskaya, Olga, Asatryan, Liana, Wyatt, Letisha, Popova, Maya, Li, Kaixun, Peoples, Robert W., Alkana, Ronald L., Davies, Daryl L.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063738/
https://ncbi.nlm.nih.gov/pubmed/21212160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.176990
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