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Purification and characterization of cystathionine β-synthase bearing a cobalt protoporphyrin

Human cystathionine β-synthase (CBS), a pivotal enzyme in the metabolism of homocysteine, is a pyridoxal-5′-phosphate-dependent enzyme that also contains heme, a second cofactor whose function is still unclear. One strategy for elucidation of heme function is its replacement with different metallopo...

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Hlavní autoři: Majtan, Tomas, Freeman, Katherine M., Smith, Aaron T., Burstyn, Judith N., Kraus, Jan P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063419/
https://ncbi.nlm.nih.gov/pubmed/21262193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2011.01.012
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