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The alternative pathway is required, but not alone sufficient, for retinal pathology in mouse laser-induced choroidal neovascularization
Human genetic studies have demonstrated that polymorphisms in different complement proteins can increase the risk for developing AMD. There are three pathways of complement activation, classical (CP), alternative (AP), and lectin (LP), which all activate a final common pathway. Proteins encoded by t...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3063365/ https://ncbi.nlm.nih.gov/pubmed/21257205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2010.12.016 |
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