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2,3-Substituted quinoxalin-6-amine analogs as antiproliferatives: A structure activity relationship study

The quinoxaline core is considered a privileged scaffold as it is found in a variety of biologically relevant molecules. Here we report the synthesis of a quinoxalin-6-amine library, screening against a panel of cancer cell lines and a structure activity relationship (SAR). This resulted in the iden...

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Detalhes bibliográficos
Main Authors: Chen, Qianyi, Bryant, Vashti C., Lopez, Hernando, Kelly, David L., Luo, Xu, Natarajan, Amarnath
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063321/
https://ncbi.nlm.nih.gov/pubmed/21376584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.02.055
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