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Synthesis and Evaluation of Macrocyclic Diarylether Heptanoid Natural Products and their Analogs

The macrocyclic diarylether heptanoid (MDEH) natural products have been used in folk medicine for centuries. MDEHs are reported to exert anti-tumor properties by inhibiting the activation of NF-κB. Here we report the synthesis of a small MDEH library (first reported synthesis of racemic platycarynol...

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Detalhes bibliográficos
Main Authors: Bryant, Vashti C., Kishore Kumar, G. D., Nyong, Abijah M., Natarajan, Amarnath
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248982/
https://ncbi.nlm.nih.gov/pubmed/22137846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.11.025
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