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Unconventional Macrocyclizations in Natural Product Synthesis

[Image: see text] Over the past several decades, macrocyclic compounds have emerged as increasingly significant therapeutic candidates in drug discovery. Their pharmacological activity hinges on their rotationally restricted three-dimensional orientation, resulting in a unique conformational preorga...

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Detalhes bibliográficos
Publicado no:ACS Cent Sci
Main Authors: Saridakis, Iakovos, Kaiser, Daniel, Maulide, Nuno
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7706100/
https://ncbi.nlm.nih.gov/pubmed/33274267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.0c00599
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