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Synthesis and Evaluation of Macrocyclic Diarylether Heptanoid Natural Products and their Analogs

The macrocyclic diarylether heptanoid (MDEH) natural products have been used in folk medicine for centuries. MDEHs are reported to exert anti-tumor properties by inhibiting the activation of NF-κB. Here we report the synthesis of a small MDEH library (first reported synthesis of racemic platycarynol...

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Hlavní autoři: Bryant, Vashti C., Kishore Kumar, G. D., Nyong, Abijah M., Natarajan, Amarnath
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248982/
https://ncbi.nlm.nih.gov/pubmed/22137846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.11.025
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