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Glutamate carboxypeptidase activity in human skin biopsies as a pharmacodynamic marker for clinical studies
BACKGROUND: Glutamate excitotoxicity is thought to be involved in the pathogenesis of neurodegenerative disease. One potential source of glutamate is N-acetyl-aspartyl-glutamate (NAAG) which is hydrolyzed to glutamate and N-acetyl-aspartate (NAA) in a reaction catalyzed by glutamate carboxypeptidase...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3063219/ https://ncbi.nlm.nih.gov/pubmed/21388540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-27 |
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