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Development of a High-Throughput Fluorescence Polarization Assay to Identify Novel Ligands of Glutamate Carboxypeptidase II

Glutamate carboxypeptidase II (GCPII) is an important target for therapeutic and diagnostic interventions aimed at prostate cancer and neurologic disorders. Here we describe the development and optimization of a high-throughput screening (HTS) assay based on fluorescence polarization (FP) that facil...

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書誌詳細
主要な著者: Alquicer, Glenda, Sedlák, David, Byun, Youngjoo, Pavlíček, Jiří, Stathis, Marigo, Rojas, Camilo, Slusher, Barbara, Pomper, Martin G., Bartůněk, Petr, Bařinka, Cyril
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112551/
https://ncbi.nlm.nih.gov/pubmed/22751730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057112451924
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