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Inhibition profile of Leishmania mexicana arginase reveals differences with human arginase I
Arginase (ARG), the enzyme that catalyzes the conversion of arginine to ornithine and urea, is the first and committed step in polyamine biosynthesis in Leishmania. The creation of a conditionally lethal Δarg null mutant in Leishmania mexicana has established that ARG is an essential enzyme for the...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3062745/ https://ncbi.nlm.nih.gov/pubmed/21232540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpara.2010.12.006 |
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