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Inhibition profile of Leishmania mexicana arginase reveals differences with human arginase I

Arginase (ARG), the enzyme that catalyzes the conversion of arginine to ornithine and urea, is the first and committed step in polyamine biosynthesis in Leishmania. The creation of a conditionally lethal Δarg null mutant in Leishmania mexicana has established that ARG is an essential enzyme for the...

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Detaylı Bibliyografya
Asıl Yazarlar: Riley, Eric, Roberts, Sigrid C., Ullman, Buddy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062745/
https://ncbi.nlm.nih.gov/pubmed/21232540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpara.2010.12.006
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