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Strong CD28 costimulation suppresses induction of regulatory T cells from naive precursors through Lck signaling
CD28 costimulation is required for the generation of naturally derived regulatory T cells (nTregs) in the thymus through lymphocyte-specific protein tyrosine kinase (Lck) signaling. However, it is not clear how CD28 costimulation regulates the generation of induced Tregs (iTregs) from naive CD4 T-ce...
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| Hoofdauteurs: | , , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society of Hematology
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3062312/ https://ncbi.nlm.nih.gov/pubmed/21245484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-08-301275 |
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