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CD28 Controls Differentiation of Regulatory T Cells from Naive CD4 T Cells

CD28 is required for the development of regulatory T cells (Tregs; CD4(+)CD25(+)Foxp3(+)) in the thymus and also contributes to their survival and homeostasis in the periphery. We studied whether and how CD28 and ICOS control the differentiation of Tregs from naive T cells. By using wild-type, CD28-...

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Detalhes bibliográficos
Main Authors: Guo, Fei, Iclozan, Cristina, Suh, Woong-Kyung, Anasetti, Claudio, Yu, Xue-Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688779/
https://ncbi.nlm.nih.gov/pubmed/18684917
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