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Helios enhances the preferential differentiation of human fetal CD4(+) naïve T cells into regulatory T cells.

T cell receptor (TCR) stimulation and cytokine cues drive the differentiation of CD4(+) naïve T cells into effector T cell populations with distinct pro-inflammatory or regulatory functions. Unlike adult naïve T cells, human fetal naïve CD4(+) T cells preferentially differentiate into FOXP3(+) regul...

詳細記述

保存先:
書誌詳細
出版年:Sci Immunol
主要な著者: Ng, Melissa S. F., Roth, Theodore L., Mendoza, Ventura F., Marson, Alexander, Burt, Trevor D.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7340007/
https://ncbi.nlm.nih.gov/pubmed/31757834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aav5947
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