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Helios enhances the preferential differentiation of human fetal CD4(+) naïve T cells into regulatory T cells.
T cell receptor (TCR) stimulation and cytokine cues drive the differentiation of CD4(+) naïve T cells into effector T cell populations with distinct pro-inflammatory or regulatory functions. Unlike adult naïve T cells, human fetal naïve CD4(+) T cells preferentially differentiate into FOXP3(+) regul...
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| 出版年: | Sci Immunol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7340007/ https://ncbi.nlm.nih.gov/pubmed/31757834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aav5947 |
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