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Fetal Regulatory T Cells and Peripheral Immune Tolerance in utero: Implications for Development and Disease
The developing fetus must actively learn to tolerate benign antigens, or suffer the consequences of broken tolerance. Tolerance of self-antigens prevents development of autoimmune diseases, and is achieved by both deletion of autoreactive T cell clones in the thymus (central tolerance) and by the su...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3951896/ https://ncbi.nlm.nih.gov/pubmed/23432802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/aji.12083 |
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