Maternal Alloantigens Promote the Development of Tolerogenic Fetal Regulatory T Cells in Utero

As the immune system develops, T cells are selected or regulated to become tolerant of self antigens and reactive against foreign antigens. In mice, the induction of such tolerance is thought to be attributable to the deletion of self-reactive cells. Here, we show that the human fetal immune system...

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Hlavní autoři: Mold, Jeff E., Michaëlsson, Jakob, Burt, Trevor D., Muench, Marcus O., Beckerman, Karen P., Busch, Michael P., Lee, Tzong-Hae, Nixon, Douglas F., McCune, Joseph M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648820/
https://ncbi.nlm.nih.gov/pubmed/19056990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1164511
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