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Thermodynamic examination of the pyrophosphate sensor helix in the thiamine pyrophosphate riboswitch

Riboswitches are functional mRNA that control gene expression. Thiamine pyrophosphate (TPP) binds to thi-box riboswitch RNA and allosterically inhibits genes that code for proteins involved in the biosynthesis and transport of thiamine. Thiamine binding to the pyrimidine sensor helix and pyrophospha...

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Bibliografiske detaljer
Main Authors: Furniss, Stephanie, Grover, Neena
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062181/
https://ncbi.nlm.nih.gov/pubmed/21367973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2263211
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