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Thermodynamic examination of the pyrophosphate sensor helix in the thiamine pyrophosphate riboswitch
Riboswitches are functional mRNA that control gene expression. Thiamine pyrophosphate (TPP) binds to thi-box riboswitch RNA and allosterically inhibits genes that code for proteins involved in the biosynthesis and transport of thiamine. Thiamine binding to the pyrimidine sensor helix and pyrophospha...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3062181/ https://ncbi.nlm.nih.gov/pubmed/21367973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2263211 |
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