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Direct Observation of Multiple Tautomers of Oxythiamine and their Recognition by the Thiamine Pyrophosphate Riboswitch

Structural diversification of canonical nucleic acid bases and nucleotide analogues by tautomerism has been proposed to be a powerful on/off switching mechanism allowing regulation of many biological processes mediated by RNA enzymes and aptamers. Despite the suspected biological importance of tauto...

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Detalhes bibliográficos
Main Authors: Singh, Vipender, Peng, Chunte Sam, Li, Deyu, Mitra, Koyel, Silvestre, Katherine J., Tokmakoff, Andrei, Essigmann, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956446/
https://ncbi.nlm.nih.gov/pubmed/24252063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400581f
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