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Direct Observation of Multiple Tautomers of Oxythiamine and their Recognition by the Thiamine Pyrophosphate Riboswitch

Structural diversification of canonical nucleic acid bases and nucleotide analogues by tautomerism has been proposed to be a powerful on/off switching mechanism allowing regulation of many biological processes mediated by RNA enzymes and aptamers. Despite the suspected biological importance of tauto...

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Détails bibliographiques
Auteurs principaux: Singh, Vipender, Peng, Chunte Sam, Li, Deyu, Mitra, Koyel, Silvestre, Katherine J., Tokmakoff, Andrei, Essigmann, John M.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956446/
https://ncbi.nlm.nih.gov/pubmed/24252063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400581f
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