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Folding energy landscape of the thiamine pyrophosphate riboswitch aptamer

Riboswitches are motifs in the untranslated regions (UTRs) of RNA transcripts that sense metabolite levels and modulate the expression of the corresponding genes for metabolite import, export, synthesis, or degradation. All riboswitches contain an aptamer: an RNA structure that, upon binding ligand,...

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Bibliografiske detaljer
Main Authors: Anthony, Peter C., Perez, Christian F., García-García, Cuauhtémoc, Block, Steven M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277107/
https://ncbi.nlm.nih.gov/pubmed/22219369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115045109
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