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Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch
Riboswitches are metabolite-sensing RNAs, typically located in the non-coding portions of messenger RNAs, that control the synthesis of metabolite-related proteins(1–3). Here we describe a 2.05 Å crystal structure of a riboswitch domain from the Escherichia coli thiM mRNA(4) that responds to the coe...
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| Udgivet i: | Nature |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4689313/ https://ncbi.nlm.nih.gov/pubmed/16728979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature04740 |
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