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Structural insights into ligand recognition by a sensing domain of the cooperative glycine riboswitch

Glycine riboswitches regulate gene expression by feedback modulation in response to cooperative binding to glycine. Here, we report on crystal structures of the second glycine-sensing domain from the V. cholerae riboswitch in the ligand-bound and unbound states. This domain adopts a three-helical fo...

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Détails bibliographiques
Auteurs principaux: Huang, Lili, Serganov, Alexander, Patel, Dinshaw J.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726718/
https://ncbi.nlm.nih.gov/pubmed/21145485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.11.026
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