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Thermodynamic analysis of ligand binding and ligand binding-induced tertiary structure formation by the thiamine pyrophosphate riboswitch

The thi-box riboswitch regulates gene expression in response to the intracellular concentration of thiamine pyrophosphate (TPP) in archaea, bacteria, and eukarya. To complement previous biochemical, genetic, and structural studies of this phylogenetically widespread RNA domain, we have characterized...

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Détails bibliographiques
Auteurs principaux: Kulshina, Nadia, Edwards, Thomas E., Ferré-D'Amaré, Adrian R.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802028/
https://ncbi.nlm.nih.gov/pubmed/19948769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1847310
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