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Analysis of riboswitch structure and ligand binding using small-angle X-ray scattering (SAXS)

Small-angle X-ray scattering (SAXS) is a powerful tool for examining the global conformation of riboswitches in solution, and how this is modulated by binding of divalent cations and small molecule ligands. SAXS experiments, which typically require only minutes per sample, directly yield two quantit...

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Main Authors: Baird, Nathan J., Ferré-D'Amaré, Adrian R.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049135/
https://ncbi.nlm.nih.gov/pubmed/24318897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-730-3_16
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