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Idiosyncratically tuned switching behavior of riboswitch aptamer domains revealed by comparative small-angle X-ray scattering analysis

Riboswitches are structured mRNA elements that regulate gene expression upon binding specific cellular metabolites. It is thought that the highly conserved metabolite-binding domains of riboswitches undergo conformational change upon binding their cognate ligands. To investigate the generality of su...

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Detalhes bibliográficos
Main Authors: Baird, Nathan J., Ferré-D'Amaré, Adrian R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822924/
https://ncbi.nlm.nih.gov/pubmed/20106958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1852310
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