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Thermodynamic analysis of ligand binding and ligand binding-induced tertiary structure formation by the thiamine pyrophosphate riboswitch

The thi-box riboswitch regulates gene expression in response to the intracellular concentration of thiamine pyrophosphate (TPP) in archaea, bacteria, and eukarya. To complement previous biochemical, genetic, and structural studies of this phylogenetically widespread RNA domain, we have characterized...

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Autori principali: Kulshina, Nadia, Edwards, Thomas E., Ferré-D'Amaré, Adrian R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802028/
https://ncbi.nlm.nih.gov/pubmed/19948769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1847310
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