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Allosteric tertiary interactions pre-organize the c-di-GMP riboswitch and accelerate ligand binding

Cyclic diguanylate (c-di-GMP) is a bacterial second messenger important for physiologic adaptation and virulence. Class-I c-di-GMP riboswitches are phylogenetically widespread and thought to mediate pleiotropic genetic responses to the second messenger. Previous studies suggest that the RNA aptamer...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wood, Sharla, Ferré-D’Amaré, Adrian R., Rueda, David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356476/
https://ncbi.nlm.nih.gov/pubmed/22380737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300014u
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