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Basal Cell Carcinomas Arise From Hair Follicle Stem Cells in Ptch1+/− Mice
Basal cell carcinomas (BCCs) are hedgehog-driven tumors that resemble follicular and interfollicular epidermal basal keratinocytes and hence long have been thought to arise from these cells. However, the actual cell of origin is unknown. Using cell fate tracking of X-ray induced BCCs in Ptch1+/− mic...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061401/ https://ncbi.nlm.nih.gov/pubmed/21215705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2010.11.007 |
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