Hair Follicle Disruption Facilitates Pathogenesis to UVB-Induced Cutaneous Inflammation and Basal Cell Carcinoma Development in Ptch(+/−) Mice

Hairless mice carrying homozygous mutations in hairless gene manifest rudimentary hair follicles (HFs), epidermal cysts, hairless phenotype, and enhanced susceptibility to squamous cell carcinomas. However, their susceptibility to basal cell carcinomas (BCCs), a neoplasm considered originated from H...

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Detalhes bibliográficos
Main Authors: Xu, Jianmin, Weng, Zhiping, Arumugam, Aadithya, Tang, Xiuwei, Chaudhary, Sandeep C., Li, Changzhao, Christiano, Angela M., Elmets, Craig A., Bickers, David R., Athar, Mohammad
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005987/
https://ncbi.nlm.nih.gov/pubmed/24631180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.01.013
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