Nitric Oxide-releasing Sulindac is a Novel Skin Cancer Chemopreventive Agent for UVB-induced Photocarcinogenesis

Nitric oxide (NO)-releasing non-steroidal anti-inflammatory drugs (NO-NSAIDs) which have been synthesized to reduce gastro-intestinal and cardiovascular toxicities of NSAIDs, possess anti-proliferative, pro-apoptotic and anti-cancer activities. Here, we show that NO-sulindac inhibited UVB-induced sk...

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Detalhes bibliográficos
Main Authors: Chaudhary, Sandeep C., Singh, Tripti, Kapur, Puneet, Weng, Zhiping, Arumugam, Aadithya, Elmets, Craig A., Kopelovich, Levy, Athar, Mohammad
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780591/
https://ncbi.nlm.nih.gov/pubmed/23274568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2012.12.009
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