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Directed adenovirus evolution using engineered mutator viral polymerases
Adenoviruses (Ads) are the most frequently used viruses for oncolytic and gene therapy purposes. Most Ad-based vectors have been generated through rational design. Although this led to significant vector improvements, it is often hampered by an insufficient understanding of Ad’s intricate functions...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061072/ https://ncbi.nlm.nih.gov/pubmed/21138963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1258 |
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