Directed adenovirus evolution using engineered mutator viral polymerases

Adenoviruses (Ads) are the most frequently used viruses for oncolytic and gene therapy purposes. Most Ad-based vectors have been generated through rational design. Although this led to significant vector improvements, it is often hampered by an insufficient understanding of Ad’s intricate functions...

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Detalhes bibliográficos
Main Authors: Uil, Taco G., Vellinga, Jort, de Vrij, Jeroen, van den Hengel, Sanne K., Rabelink, Martijn J. W. E., Cramer, Steve J., Eekels, Julia J. M., Ariyurek, Yavuz, van Galen, Michiel, Hoeben, Rob C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061072/
https://ncbi.nlm.nih.gov/pubmed/21138963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1258
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