Antibody responses after intravaginal immunisation with trimeric HIV-1(CN54) clade C gp140 in Carbopol gel are augmented by systemic priming or boosting with an adjuvanted formulation

Optimum strategies to elicit and maintain antibodies at mucosal portals of virus entry are critical for the development of vaccines against human immunodeficiency virus (HIV). Here we show in non-human primates that a novel regimen of repeated intravaginal delivery of a non-adjuvanted, soluble recom...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Cranage, Martin P., Fraser, Carol A., Cope, Alethea, McKay, Paul F., Seaman, Michael S., Cole, Tom, Mahmoud, A. Nasir, Hall, Joanna, Giles, Elaine, Voss, Gerald, Page, Mark, Almond, Neil, Shattock, Robin J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Science 2011
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060343/
https://ncbi.nlm.nih.gov/pubmed/21187177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.12.034
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky